Researchers long thought that only one strand of a double-stranded microRNA can silence genes. Though recent evidence has challenged that dogma, it's unclear what the other strand does, and how the two may be involved in cancer. New research from…
Bioengineers create light-controllable CAR T cells for cancer immunotherapy
Bioengineers at the University of California San Diego have developed a control system that could make CAR T-cell therapy safer and more powerful when treating cancer. By programming CAR T cells to switch on when exposed to blue light, the…
Single gene cluster loss promotes initiation and progression of multiple myeloma in mice
Bottom Line: The loss of one copy of the miR15a/miR16-1 gene cluster promoted initiation and progression of multiple myeloma in mice. Journal in Which the Study was Published: Published online in Blood Cancer Discovery, the latest journal of the American…
Researchers identify a protein that aids in colorectal cancer metastasis
A protein that helps colorectal cancer cells spread to other parts of the body could be an effective treatment target. Colorectal cancer patients with an immune system-regulating protein called interleukin 6 (IL-6) are more likely to have recurring tumors that…