Both strands of microRNA cooperate to drive cancer growth and aggressiveness, research shows

Researchers long thought that only one strand of a double-stranded microRNA can silence genes. Though recent evidence has challenged that dogma, it's unclear what the other strand does, and how the two may be involved in cancer. New research from…

Bioengineers create light-controllable CAR T cells for cancer immunotherapy

Bioengineers at the University of California San Diego have developed a control system that could make CAR T-cell therapy safer and more powerful when treating cancer. By programming CAR T cells to switch on when exposed to blue light, the…

Single gene cluster loss promotes initiation and progression of multiple myeloma in mice

Bottom Line: The loss of one copy of the miR15a/miR16-1 gene cluster promoted initiation and progression of multiple myeloma in mice. Journal in Which the Study was Published: Published online in Blood Cancer Discovery, the latest journal of the American…

New project aims to gain insights into bone metastasis in breast cancer patients

A new project just launched at Karl Landsteiner University of Health Sciences in Krems (KL Krems) aims at gaining insights into the development of bone metastases in breast cancer patients and identifying biomarkers as well as new treatment strategies. A…

Researchers design new drug cocktail to kill brain and soft tissue cancers

Researchers at the USC Viterbi School of Engineering have designed a new drug cocktail that kills some types of brain and soft tissue cancers by tricking the cancer cells to behave as if they were starving for their favorite food–glucose.…

Researchers identify a protein that aids in colorectal cancer metastasis

A protein that helps colorectal cancer cells spread to other parts of the body could be an effective treatment target. Colorectal cancer patients with an immune system-regulating protein called interleukin 6 (IL-6) are more likely to have recurring tumors that…